PRODUCTION OF CXC AND CC CHEMOKINES BY HUMAN ANTIGEN-PRESENTING CELLS IN RESPONSE TO LASSA VIRUS OR CLOSELY RELATED IMMUNOGENIC VIRUSES, AND IN CYNOMOLGUS MONKEYS WITH LASSA FEVER.

The pathogenesis of Lassa fever (LF), a hemorrhagic fever Pipe Parts endemic to West Africa, remains unclear.We previously compared Lassa virus (LASV) with its genetically close, but nonpathogenic homolog Mopeia virus (MOPV) and demonstrated that the strong activation of antigen-presenting cells (APC), including type I IFN production, observed in r

Endometriosis is defined as the presence of ectopic endometrial tissue outside the uterus.It is a common disease in menstruating females and intestinal involvement is not uncommon.Intestinal endometriosis most Silhouettes commonly involves the sigmoid colon, rectum, ileum, appendix, and cecum.However, the descending colon is a rare site of intestin

ObjectivesA subset of non-functioning pituitary macroadenomas (NFMAs) may exhibit early progression/recurrence (P/R) after tumor resection.The purpose of this study was to apply deep learning (DL) algorithms for prediction of P/R in NFMAs.MethodsFrom June 2009 to December 2019, 78 patients diagnosed with pathologically confirmed NFMAs, and who had

Abstract Background There has been rapid development of probabilistic models and inference methods for transcript abundance estimation from RNA-seq data.These models aim to accurately estimate transcript-level abundances, to account for different biases in the measurement process, and even to assess uncertainty in resulting estimates that can be pr

Although Colombia presents an enormous biological diversity, few studies have been conducted on the population genetics of Trypanosoma cruzi.This study was carried out with 23 Colombian stocks of this protozoa analyzed for 13 isoenzymatic loci.The Hardy-Weinberg equilibrium, the genetic diversity and heterogeneity, the genetic relationships and the